Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw
Taiwan ODM expert for comfort products
Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Indonesia graphene material ODM solution
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Innovative insole ODM solutions in Indonesia
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Ergonomic insole ODM support Taiwan
📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.China eco-friendly graphene material processing
Research on sea lampreys offers insights into vertebrate evolution, highlighting similarities in stem cell gene networks with jawed vertebrates and explaining differences in jaw formation. Credit: T. Lawrence, Great Lakes Fishery CommissionA These invasive, blood-sucking fish “may hold the key to understanding where we came from.” One of only two jawless vertebrates, sea lampreys, which are causing significant damage to Midwestern fisheries, are also aiding scientists in understanding the origins of two crucial stem cells that played a key role in the evolution of vertebrates. Northwestern University biologists have pinpointed when the gene network that regulates these stem cells may have evolved and gained insights into what might be responsible for lampreys’ missing mandibles. The two cell types — pluripotent blastula cells (or embryonic stem cells) and neural crest cells — are both “pluripotent,” which means they can become all other cell types in the body. In a new paper, researchers compared lamprey genes to those of the Xenopus, a jawed aquatic frog. Using comparative transcriptomics, the study revealed a strikingly similar pluripotency gene network across jawless and jawed vertebrates, even at the level of transcript abundance for key regulatory factors. Differences in Gene Expression But the researchers also discovered a key difference. While both species’ blastula cells express the pou5 gene, a key stem cell regulator, the gene is not expressed in neural crest stem cells in lampreys. Losing this factor may have limited the ability of neural crest cells to form cell types found in jawed vertebrates (animals with spines) that make up the head and jaw skeleton. The study was recently published in the journal Nature Ecology & Evolution. By comparing the biology of jawless and jawed vertebrates, researchers can gain insight into the evolutionary origins of features that define vertebrate animals including humans, how differences in gene expression contribute to key differences in the body plan, and what the common ancestor of all vertebrates looked like. “Lampreys may hold the key to understanding where we came from,” said Northwestern’s Carole LaBonne, who led the study. “In evolutionary biology, if you want to understand where a feature came from, you can’t look forward to more complex vertebrates that have been evolving independently for 500 million years. You need to look backward to whatever the most primitive version of the type of animal you’re studying is, which leads us back to hagfish and lampreys — the last living examples of jawless vertebrates.” An expert in developmental biology, LaBonne is a professor of molecular biosciences at the Weinberg College of Arts and Sciences. She holds the Erastus Otis Haven Chair and is part of the leadership of the National Science Foundation’s (NSF) new Simons National Institute for Theory and Mathematics in Biology. LaBonne and her colleagues previously demonstrated that the developmental origin of neural crest cells was linked to retaining the gene regulatory network that controls pluripotency in blastula stem cells. In the new study, they explored the evolutionary origin of the links between these two stem cell populations. Significance of Neural Crest Cells “Neural crest stem cells are like an evolutionary Lego set,” said LaBonne. “They become wildly different types of cells, including neurons and muscle, and what all those cell types have in common is a shared developmental origin within the neural crest.” While blastula-stage embryonic stem cells lose their pluripotency and become confined to distinct cell types fairly rapidly as an embryo develops, neural crest cells hold onto the molecular toolkit that controls pluripotency later into development. LaBonne’s team found a completely intact pluripotency network within lamprey blastula cells, stem cells whose role within jawless vertebrates had been an open question. This implies that blastula and neural crest stem cell populations of jawed and jawless vertebrates co-evolved at the base of vertebrates. Northwestern postdoctoral fellow and first author Joshua York observed “more similarities than differences” between the lamprey and Xenopus. “While most of the genes controlling pluripotency are expressed in the lamprey neural crest, the expression of one of these key genes — pou5 — was lost from these cells,” York said. “Amazingly, even though pou5 isn’t expressed in a lamprey’s neural crest, it could promote neural crest formation when we expressed it in frogs, suggesting this gene is part of an ancient pluripotency network that was present in our earliest vertebrate ancestors.” The experiment also helped them hypothesize that the gene was specifically lost in certain creatures, not something jawed vertebrates developed later on. “Another remarkable finding of the study is that even though these animals are separated by 500 million years of evolution, there are stringent constraints on expression levels of genes needed to promote pluripotency,” LaBonne said. “The big unanswered question is, why?” Reference: “Shared features of blastula and neural crest stem cells evolved at the base of vertebrates” by Joshua R. York, Anjali Rao, Paul B. Huber, Elizabeth N. Schock, Andrew Montequin, Sara Rigney and Carole LaBonne, 26 July 2024, Nature Ecology & Evolution. DOI: 10.1038/s41559-024-02476-8 The paper was funded by the National Institutes of Health (grants R01GM116538 and F32DE029113), the NSF (grant 1764421), the Simons Foundation (grant SFARI 597491-RWC) and the Walder Foundation through the Life Sciences Research Foundation. The study is dedicated to the memory of Dr. Joseph Walder.
The aquarium system in which scientists submitted Northern red sea corals to various temperatures. Credit: Maoz Fine EPFL scientists are beginning to understand why corals in the Gulf of Aqaba, along with their symbiotic algae and bacteria, resist higher temperatures particularly well. Even under the most optimistic scenarios, most of the coral reef ecosystems on our planet — whether in Australia, the Maldives, or the Caribbean — will have disappeared or be in very bad shape by the end of this century. That’s because global warming is pushing ocean temperatures above the limit that single-cell algae, which are corals’ main allies, can withstand. These algae live inside coral tissue for protection and, in exchange, provide corals with essential nutrients produced through photosynthesis. Because the algae contain a variety of pigments and therefore give coral reefs their famous colors, if they are lost the corals turn white, which is known as coral bleaching. But in spite of the real threat caused by global warming, corals in the Red Sea look set to keep their vibrant color. “We already knew that corals in the Gulf of Aqaba, at the northern tip of the Red Sea, were particularly resistant to higher temperatures. But we wanted to study the full molecular mechanism behind this resistance,” says Romain Savary, a postdoc at EPFL’s Laboratory for Biological Geochemistry (LGB) and lead author of the study, which appears today in PNAS. What the scientists found was telling: those corals, as well as the algae and bacteria they live in symbiosis with, can withstand average temperatures some 5°C (9°F) higher than what they typically experience. And despite the severity with which climate change is taking place, it’s unlikely that Red Sea temperatures will rise more than 5°C by the end of the century. “This gives us real hope that we can save at least one major coral reef ecosystem for future generations,” says Anders Meibom, head of the LGB. The aquarium system in which scientists submitted Northern red sea corals to various temperatures. Credit: Maoz Fine Taking it in stride To conduct their study, the scientists subjected Gulf of Aqaba corals to a range of heat stresses including the higher temperatures likely to occur in the coming decades. The average maximum monthly temperature in these waters is currently around 27°C (80.6°F), so the scientists exposed coral samples to temperatures of 29.5°C (85.1°F), 32°C (89.6°F), and 34.5°C (94.1°F), over both a short time period (three hours) and a longer one (one week). The scientists measured the corals’ and symbiotic algae’s gene expression both during and after the heat stress test, and determined the composition of the microbiome residing in the corals. “The main thing we found is that these corals currently live in temperatures well below the maximum they can withstand with their molecular machinery, which means they’re naturally shielded against the temperature increases that will probably occur over the next 100 or even 200 years,” says Savary. “Our measurements showed that at temperatures of up to 32°C, the corals and their symbiotic organisms were able to molecularly recover and acclimate to both short-term and long-term heat stress without any major consequences.” This offers genuine hope to scientists — although warmer waters are not the only threat facing this exceptional natural heritage. Corals in the Gulf of Aqaba, at the northern tip of the Red Sea, are particularly resistant to higher temperatures. Credit: Romain Savary/EPFL This is the first time scientists have conducted a genetic analysis of coral samples on such a broad scale, and their findings reveal how these heat-resistant corals respond at the most fundamental level — gene expression. They can also be used as a basis for identifying ‘super corals.’ According to Meibom, “Romain’s research gives us insight into the specific genetic factors that allow corals to survive. His study also indicates that an entire symphony of genetic expression is at work to give corals this extraordinary power.” This sets a standard for what “super coral” gene expression looks like during a heat stress and a recovery. But could Red Sea corals be used to one day repopulate the Great Barrier Reef? “Corals are highly dependent on their surroundings,” says Meibom. “They can adapt to new environments only after a long, natural colonization process. What’s more, the Great Barrier Reef is the size of Italy — it would be impossible to repopulate it artificially.” Sailing towards the future The scientists’ work was made possible thanks to two unique research instruments: the Red Sea Simulator (RSS), developed by the Interuniversity Institute for Marine Sciences in Eilat, Israel; and the Coral Bleaching Automated Stress System (CBASS), developed by a team of researchers in the US. Their findings have laid the groundwork for a much more ambitious project that will be led by the Transnational Red Sea Center (TRSC), which was set up at EPFL in 2019. This new project will kick off this summer and take place over four years. “We’ll sail the entire Red Sea — some 2,000 km (1,240 mi) long — on the research vessel Fleur de Passion, owned by our partner the Fondation Pacifique,” says Meibom. “The goal will be to map the heat tolerance levels and the diversity of all the different types of corals found in these waters. Water temperatures rise as you head further south on the Red Sea, with a 5-6°C (9-10.8°F) differential between the northern and southern tips. That’s what makes it a perfect real-world laboratory for studying these ecosystems. It’s as if you’re sailing towards the future as you head south.” And what does that glimpse into the future tell us? Some corals in the southern Red Sea are already starting to bleach. Savary believes there’s just one solution: “We have to protect these corals and shield them from local stressors, which are mainly sources of pollution and physical destruction. That way we can keep a stock of ‘natural super corals’ for potentially recolonizing areas that have been hit particularly hard by climate-change-induced heat waves.” Reference: “Fast and pervasive transcriptomic resilience and acclimation of extremely heat-tolerant coral holobionts from the northern Red Sea” by Romain Savary, Daniel J. Barshis, Christian R. Voolstra, Anny Cárdenas, Nicolas R. Evensen, Guilhem Banc-Prandi, Maoz Fine and Anders Meibom, 3 May 2021, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2023298118
Columbia team designs high-performance, implantable system that can manipulate brain signals and suppress pathological coupling; successfully tested in epileptic animal models, the new design could improve treatment of neuropsychiatric disorders. As researchers learn more about the brain, it has become clear that responsive neurostimulation is becoming increasingly effective at probing neural circuit function and treating neuropsychiatric disorders, such as epilepsy and Parkinson’s disease. But current approaches to designing a fully implantable and biocompatible device able to make such interventions have major limitations: their resolution isn’t high enough and most require large, bulky components that make implantation difficult with risk of complications. A Columbia Engineering team led by Dion Khodagholy, assistant professor of electrical engineering, has come up with a new approach that shows great promise to improve such devices. Building on their earlier work to develop smaller, more efficient conformable bioelectronic transistors and materials, the researchers orchestrated their devices to create high performance implantable circuits that enable allow reading and manipulation of brain circuits. Their multiplex-then-amplify (MTA) system requires only one amplifier per multiplexer, in contrast to current approaches that need an equal number of amplifiers as number of channels. Simplified schematic of the overall placement and location of the MTA in a rat. Credit: Zifang Zhao and Claudia Cea/Columbia Engineering “It is critical to be able to detect and intervene to treat brain-disorder-related symptoms, such as epileptic seizures, in real time,” said Khodagholy, a leader in bio- and neuroelectronics design. “Not only is our system much smaller and more flexible than current devices, but it also enables simultaneous stimulation of arbitrary waveforms on multiple independent channels, so it is much more versatile. Khodagholy collaborated on the study, published today (May 10, 2021) by Proceedings of the National Academy of Sciences (PNAS), with Jennifer N. Gelinas, Department of Neurology and the Institute for Genomic Medicine at Columbia University Irving Medical Center. Gelinas is a neuroscientist and specialist in pediatric epilepsy whose research focuses on understanding how neural networks become abnormal in epilepsy and designing methods to correct this dysfunction. In order to record, detect, and localize epileptic discharges, scientists must log brain activity in multiple locations with high temporal resolution. This requires a high-sampling-rate multi-channel acquisition and stimulation device and circuit. Conventional circuits need an equal number of amplifying circuits as number of channels before they can combine these signals into a stream of data using multiplexing. This increases the size of the circuits linearly with the number of channels. Micrograph of the micro-fabricated conformable conducting polymer-based electrode array. Credit: Zifang Zhao and Claudia Cea/Columbia Engineering Khodagholy knew from working with neurologists like Gelinas that there was a great need for an all-in-one, fully implantable system that can record, process, and stimulate brain activity — such a system would enable researchers to design personalized therapies. To record brain activity, he needed multi-channel amplifiers but the available options were too big and unwieldy. As the team continued to make their electrodes more effective, lowering impedance by using a conducting polymer, they suddenly wondered what would happen if they took advantage of their electrode improvements in circuit design and placed the multiplexer in front of, rather than after, the amplifier. With this new idea in mind, the team built the MTA device and then confirmed its functionality by developing a fully implantable, responsive embedded system that can acquire — in real time — individual neural action potentials using conformable conducting polymer-based electrodes. It can accomplish this with low-latency arbitrary waveform stimulation and local data storage — all within a miniaturized (approximately the size of a quarter) physical footprint. “The key challenge was to create an electric-charge drainage path during the multiplexing operation to eliminate any unwanted charge accumulation,” said Zifang Zhao, postdoctoral fellow in the department of electrical engineering and the first author of the study. The MTA device, which was fabricated at the Columbia Nano-Initiative, enabled the team to then develop a novel closed-loop protocol to suppress pathological coupling between the hippocampus and cortex in real-time within an epileptic network. This type of approach could help address memory problems that often accompany epilepsy. “These devices will allow application of targeted high-spatiotemporal resolution responsive neurostimulation approaches to a variety of brain functions, greatly broadening our ability to chronically modify neural networks and treat neuropsychiatric disease,” Gelinas said. The team is now integrating their system with various experimental platforms with the goal of improving neural network function and cognitive skills. Reference: “Responsive manipulation of neural circuit pathology by fully implantable, front-end multiplexed embedded neuroelectronics” by Zifang Zhao, Claudia Cea, Jennifer N. Gelinas and Dion Khodagholy, 10 May 2021, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2022659118 Funding: National Science Foundation EAGER, National Science Foundation CAREER, CURE Taking Flight Award, Columbia School of Engineering
DVDV1551RTWW78V
Thailand insole ODM for global brands 》your trusted source for functional product developmentChina pillow ODM development service 》manufacturing with a focus on sustainability and comfortInsole ODM factory in Vietnam 》elevating your brand with precision engineering and flexible production